Table 3.
Relations of peripheral myeloid-derived suppressor cells and regulatory T cells with blast cells in children with B-cell acute lymphoblastic leukemia.
| Cells | PB blast cells | BM blast cells | CD34+ cells |
|---|---|---|---|
| Total MDSC | r = 0.1 | r = 0.1 | r = 0.07 |
| p = 0.3 | p = 0.2 | p = 0.4 | |
| PMN–MDSCs | r = 0.4 | r = 0.4 | r = 0.5 |
| p = 0.007 | p = 0.006 | p = 0.001 | |
| MO-MDSCs | r = − 0.2 | r = − 0.2 | r = − 0.2 |
| p = 0.1 | p = 0.1 | p = 0.06 | |
| CD4+T cells | r = − 0.2 | r = − 0.1 | r = − 0.3 |
| p = 0.2 | p = 0.2 | p = 0.03 | |
| CD4+CD25+low | r = 0.2 | r = 0.3 | r = 0.3 |
| p = 0.1 | p = 0.08 | p = 0.03 | |
| CD4+CD25+high | r = − 0.2 | r = − 0.07 | r = − 0.2 |
| p = 0.2 | p = 0.4 | p = 0.2 | |
| CD4+CD25+highFoxP3+ (Tregs) | r = 0.5 | r = 0.6 | r = 0.5 |
| p = 0.003 | p = 0.001 | p = 0.004 |
PB peripheral blood, BM bone marrow, MDSCs myeloid-derived suppressor cells, PMN—MDSCs: polymorphonuclear myeloid-derived suppressor cells, MO-MDSCs monocytic myeloid-derived suppressor cells, Tregs regulatory T cells. Pearson correlation, r Pearson’s correlation coefficient,
significant p-value < 0.05.