Table 4.
Cells | Complete remission (n = 23) | No complete remission (n = 8) | p-value |
---|---|---|---|
Total MDSC (%) | 3.8 ± 0.4 | 4.5 ± 1 | 0.6 |
PMN-MDSCs (%) | 89.6 ± 1 | 96.2 ± 0.5 | < 0.0001 |
MO-MDSCs (%) | 10.1 ± 0.9 | 7.2 ± 1 | 0.06 |
CD4+ (%) | 29.6 ± 1 | 27 ± 3 | 0.3 |
CD4+CD25+low (%) | 17.6 ± 0.6 | 18.3 ± 0.7 | 0.4 |
CD4+CD25+high (%) | 7 ± 0.6 | 6.7 ± 1 | 0.3 |
CD4+CD25+highFoxP3+(Tregs) (%) | 2.1 ± 0.1 | 2.8 ± 0.1 | 0.001 |
n number, MDSCs myeloid-derived suppressor cells, PMN-MDSCs polymorphonuclearmyeloid-derived suppressor cells, MO-MDSCs monocytic myeloid-derived suppressor cells, Tregs regulatory T cells. Results expressed as mean ± S.E. Mann–Whitney U test; significant p-value < 0.05.