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. 2021 Jul 22;11:15039. doi: 10.1038/s41598-021-94469-x

Table 4.

Relation of myeloid-derived suppressor cells and regulatory T cells with the post-induction response in children with B-cell acute lymphoblastic leukemia.

Cells Complete remission (n = 23) No complete remission (n = 8) p-value
Total MDSC (%) 3.8 ± 0.4 4.5 ± 1 0.6
PMN-MDSCs (%) 89.6 ± 1 96.2 ± 0.5  < 0.0001
MO-MDSCs (%) 10.1 ± 0.9 7.2 ± 1 0.06
CD4+ (%) 29.6 ± 1 27 ± 3 0.3
CD4+CD25+low (%) 17.6 ± 0.6 18.3 ± 0.7 0.4
CD4+CD25+high (%) 7 ± 0.6 6.7 ± 1 0.3
CD4+CD25+highFoxP3+(Tregs) (%) 2.1 ± 0.1 2.8 ± 0.1 0.001

n number, MDSCs myeloid-derived suppressor cells, PMN-MDSCs polymorphonuclearmyeloid-derived suppressor cells, MO-MDSCs monocytic myeloid-derived suppressor cells, Tregs regulatory T cells. Results expressed as mean ± S.E. Mann–Whitney U test; significant p-value < 0.05.