Table 1.
Baseline characteristics of patients stratified by SBP categories.
| Characteristics | Overall n = 2100 |
Baseline SBP | |||||
|---|---|---|---|---|---|---|---|
| < 120 n = 229 |
120–129 n = 348 |
130–139 n = 604 |
140–149 n = 445 |
150–159 n = 253 |
160 ≤ n = 191 |
||
| Male sex, % | 71.4 | 72.9 | 74.3 | 69.5 | 69.7 | 73.5 | 71.2 |
| Age, year | 62.5 ± 8.3 | 62.4 ± 8.7 | 61.9 ± 8.8 | 62.7 ± 8.2 | 62.3 ± 8.0 | 62.9 ± 7.7 | 63.0 ± 8.4 |
| BMI, kg/m2 | 25.7 ± 3.8 | 25.4 ± 3.7 | 25.6 ± 3.8 | 25.5 ± 3.7 | 25.8 ± 4.0 | 26.1 ± 3.7 | 25.8 ± 4.1 |
| Abdominal girth, cm | 90.0 ± 9.9 | 87.4 ± 10.7 | 89.0 ± 9.8 | 90.2 ± 9.7 | 91.2 ± 9.8 | 90.6 ± 9.1 | 91.1 ± 10.4 |
| Current smoking, % | 22.5 | 19.4 | 24.5 | 21.7 | 22.5 | 24.2 | 23.0 |
| Diabetes mellitus, % | 61.1 | 58.1 | 58.5 | 59.0 | 61.0 | 68.4 | 67.0 |
| Hypertension, % | 90.8 | 77.7 | 87.5 | 91.0 | 95.1 | 96.1 | 95.8 |
| Dyslipidemia, % | 69.3 | 66.8 | 69.5 | 69.3 | 71.2 | 72.3 | 63.4 |
| Hyperuricemia, % | 38.8 | 39.3 | 40.3 | 40.4 | 35.6 | 35.2 | 42.4 |
| Medication | |||||||
| Anti-hypertensive, % | 86.1 | 73,8 | 81.8 | 85.9 | 89.4 | 93.3 | 93.2 |
| Use of RAS-I, % | 72.8 | 65.1 | 70.9 | 70.5 | 74.6 | 79.8 | 79.6 |
| Laboratory values | |||||||
| Positive proteinuria, %a | 80.6 | 71.6 | 73.7 | 80.3 | 85.4 | 88.5 | 85.3 |
| Proteinuria, median (IQR), g/gCr | 0.22 (0.06–0.71) | 0.16 (0.05–0.39) | 0.19 (0.06–0.55) | 0.23 (0.06–0.72) | 0.26 (0.07–0.87) | 0.28 (0.10–0.85) | 0.45 (0.08–1.36) |
| Total protein, g/dL | 7.2 ± 0.5 | 7.2 ± 0.5 | 7.2 ± 0.5 | 7.3 ± 0.5 | 7.3 ± 0.5 | 7.1 ± 0.5 | 7.2 ± 0.5 |
| Albumin, g/dL | 4.3 ± 0.4 | 4.2 ± 0.3 | 4.3 ± 0.3 | 4.3 ± 0.4 | 4.3 ± 0.4 | 4.2 ± 0.4 | 4.2 ± 0.4 |
| Hemoglobin, g/dL | 13.8 ± 1.8 | 13.6 ± 1.8 | 13.9 ± 1.8 | 13.8 ± 1.8 | 13.9 ± 1.7 | 13.8 ± 1.9 | 13.6 ± 2.1 |
| BUN, mg/dL | 19.6 ± 8.0 | 20.2 ± 8.0 | 18.9 ± 7.2 | 19.5 ± 8.0 | 19.4 ± 8.1 | 19.5 ± 8.4 | 20.7 ± 8.7 |
| Creatinine, mg/dL | 1.07 ± 0.49 | 1.10 ± 0.44 | 1.05 ± 0.48 | 1.07 ± 0.48 | 1.05 ± 0.49 | 1.10 ± 0.57 | 1.16 ± 0.53 |
| eGFR, ml/min/1.73 m2 | 59.1 ± 21.9 | 57.0 ± 21.2 | 60.3 ± 21.1 | 59.0 ± 22.1 | 60.8 ± 22.2 | 59.1 ± 21.7 | 55.7 ± 22.7 |
| HbA1c, % | 6.2 ± 1.2 | 6.0 ± 1.1 | 6.1 ± 1.2 | 6.1 ± 1.1 | 6.2 ± 1.3 | 6.3 ± 1.2 | 6.3 ± 1.1 |
| Uric acid, mg/dL | 6.2 ± 1.2 | 6.2 ± 1.8 | 6.2 ± 1.5 | 6.1 ± 1.5 | 6.1 ± 1.6 | 6.0 ± 1.5 | 6.5 ± 1.8 |
| TC, mg/dL | 198 ± 35 | 193 ± 34 | 195 ± 34 | 197 ± 37 | 201 ± 37 | 195 ± 357 | 203 ± 33 |
| HDL-C, mg/dL | 54 ± 16 | 55 ± 16 | 53 ± 15 | 54 ± 15 | 56 ± 17 | 53 ± 14 | 54 ± 18 |
| Non-HDL-C, mg/dL | 147 ± 37 | 139 ± 34 | 145 ± 36 | 147 ± 37 | 149 ± 39 | 145 ± 36 | 153 ± 39 |
| Triglyceride, mg/dL | 173 ± 140 | 151 ± 98 | 170 ± 131 | 172 ± 118 | 176 ± 171 | 176 ± 136 | 202 ± 176 |
Unless otherwise specified, data are presented as the mean ± SD.
SBP systolic blood pressure, BMI body mass index, CKD chronic kidney disease, DBP diastolic blood pressure, RAS-I renin angiotensin system inhibitor, IQR interquartile range, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c, TC total cholesterol, HDL-C high density lipoprotein cholesterol.
aDipstick positive proteinuria of ± or higher.