Table 1.
Sex | Age at operation (years) | Graft diameter at implant (mm) | Diagnosis | ||||
---|---|---|---|---|---|---|---|
Patient 1 | F | 3 | 18 | Heterotaxy syndrome, unbalanced AVSD, pulmonary atresia | |||
Clinical event | Time post Fontan operation (months) | Minimum diameter (mm) | Diameter stenosis (% from implant) | Area stenosis (% from implant) | BSA (m2) | Elastic modulus (kPa) | |
MRI I | 6 | 18 | 0% | 0% | 0.64 | 13.14 | |
MRI II | 36 | 9.4 | 48% | 61% | 0.74 | 10.51 | |
MRI II | 60 | 8.8 | 51% | 63% | |||
Patient 2 | M | 2 | 16 | PA-IVS, tricuspid stenosis, HRHS | |||
Clinical event | Time post Fontan operation (months) | Minimum diameter (mm) | Diameter stenosis (% from implant) | Area stenosis (% from implant) | BSA (m2) | Elastic modulus (kPa) | |
MRI I | 6 | 6.8 | 58% | 72% | 0.53 | 16.00 | |
Catheter lab (cutting balloon angioplasty, LPA stent placement) | 7 | 5.6 | 65% | 84% | |||
MRI II | 36 | 7.9 | 51% | 72% | 0.67 | 8.00 | |
MRI III | 60 | 11.5 | 28% | 36% | |||
Patient 3 | F | 3 | 16 | HLHS, mitral atresia/aortic atresia variant | |||
Clinical event | Time post Fontan operation (months) | Minimum diameter (mm) | Diameter stenosis (% from implant) | Area stenosis (% from implant) | BSA (m2) | Elastic modulus (kPa) | |
Catheter lab (cutting balloon angioplasty, LPA stent dilation) | 5 | 6.5 | 59% | 82% | |||
MRI I | 6 | 7.1 | 56% | 79% | 0.53 | 16.00 | |
MRI II | 36 | 7.5 | 53% | 68% | 0.67 | 17.00 | |
MRI III | 60 | 10.5 | 34% | 71% | |||
Patient 4 | F | 4 | 16 | HLHS, mitral atresia/aortic atresia variant | |||
Clinical event | Time post Fontan operation (months) | Minimum diameter (mm) | Diameter stenosis (% from implant) | Area stenosis (% from implant) | BSA (m2) | Elastic modulus (kPa) | |
Catheter lab (cutting balloon angioplasty) | 5 | 3.6 | 78% | 94% | |||
MRI I | 6 | 6.8 | 58% | 79% | 0.68 | 14.72 | |
Catheter lab (cutting balloon angioplasty) | 7 | 6.6 | 59% | 80% | |||
MRI II | 36 | 8.6 | 46% | 65% | 0.83 | 13.67 |
Elastic moduli were tuned to match fraction area change deformation observed at each MRI imaging session.
AVSD atrioventricular septal defect, PA-IVS pulmonary atresia with intact ventricular septum, HRHS hypoplastic right heart syndrome, HLHS hypoplastic left heart syndrome.