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. 2021 Jul 22;6:38. doi: 10.1038/s41536-021-00148-w

Table 1.

Description of clinical data collected from patients.

Sex Age at operation (years) Graft diameter at implant (mm) Diagnosis
Patient 1 F 3 18 Heterotaxy syndrome, unbalanced AVSD, pulmonary atresia
Clinical event Time post Fontan operation (months) Minimum diameter (mm) Diameter stenosis (% from implant) Area stenosis (% from implant) BSA (m2) Elastic modulus (kPa)
MRI I 6 18 0% 0% 0.64 13.14
MRI II 36 9.4 48% 61% 0.74 10.51
MRI II 60 8.8 51% 63%
Patient 2 M 2 16 PA-IVS, tricuspid stenosis, HRHS
Clinical event Time post Fontan operation (months) Minimum diameter (mm) Diameter stenosis (% from implant) Area stenosis (% from implant) BSA (m2) Elastic modulus (kPa)
MRI I 6 6.8 58% 72% 0.53 16.00
Catheter lab (cutting balloon angioplasty, LPA stent placement) 7 5.6 65% 84%
MRI II 36 7.9 51% 72% 0.67 8.00
MRI III 60 11.5 28% 36%
Patient 3 F 3 16 HLHS, mitral atresia/aortic atresia variant
Clinical event Time post Fontan operation (months) Minimum diameter (mm) Diameter stenosis (% from implant) Area stenosis (% from implant) BSA (m2) Elastic modulus (kPa)
Catheter lab (cutting balloon angioplasty, LPA stent dilation) 5 6.5 59% 82%
MRI I 6 7.1 56% 79% 0.53 16.00
MRI II 36 7.5 53% 68% 0.67 17.00
MRI III 60 10.5 34% 71%
Patient 4 F 4 16 HLHS, mitral atresia/aortic atresia variant
Clinical event Time post Fontan operation (months) Minimum diameter (mm) Diameter stenosis (% from implant) Area stenosis (% from implant) BSA (m2) Elastic modulus (kPa)
Catheter lab (cutting balloon angioplasty) 5 3.6 78% 94%
MRI I 6 6.8 58% 79% 0.68 14.72
Catheter lab (cutting balloon angioplasty) 7 6.6 59% 80%
MRI II 36 8.6 46% 65% 0.83 13.67

Elastic moduli were tuned to match fraction area change deformation observed at each MRI imaging session.

AVSD atrioventricular septal defect, PA-IVS pulmonary atresia with intact ventricular septum, HRHS hypoplastic right heart syndrome, HLHS hypoplastic left heart syndrome.