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. 2021 Jul 22;7:61. doi: 10.1038/s41522-021-00232-5

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© The Author(s) 2021, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Longitudinal changes of viral loads in throat swab samples and fecal specimens from COVID-19 patients. Day 0 indicated the negative conversion time of SARS-CoV-2 RNA. The red line and blue line indicated longitudinal changes in viral loads represented by the abundances of the E gene and N gene, respectively. b Boxplots showing unweighted UniFrac distances within and between groups. c The longitudinal viral load represented by the abundances of the E gene significantly correlated with the timepoint-matched relative abundances of different taxa in throat swab and fecal samples separately. p-values were obtained using CCLasso.