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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Am J Geriatr Psychiatry. 2021 Jan 23;29(12):1188–1198. doi: 10.1016/j.jagp.2021.01.004

Figure 1. Association between fractional anisotropy (FA) and baseline neurocognitive function.

Figure 1.

Clusters in which FA was significantly positively associated with executive function as measured by I/P subscale of the DRS in LLD patients (TFCE, FWE-corrected p<0.05). Regions showing clusters are overlaid on the mean FA skeleton (green) and MNI152 T1 images. The results are “thickened” using tbss_fill script in TBSS toolbox and displayed in radiological orientation. Abbreviations: I/P subscale of DRS: Initiation/Perseveration subscale of the Dementia Rating Scale, LLD: late-life depression, TFCE: threshold-free cluster enhancement, FWE: family-wise error, TBSS: tract-based spatial statistics, CST: corticospinal tract, SLF: superior longitudinal fasciculus, SLF-temporal: superior longitudinal fasciculus temporal, Left: left hemisphere, Right: right hemisphere.