Table 1.

Baseline and post treatment (Week 8) subject characteristics across demographic, clinical, and neurocognitive measures

Demographics
Characteristic	n			Mean ± SD or %
Age	71			69.4 ± 6.95
Sex
Male	24			33.8
Female	47			66.2
Race
Asian	1			1.4
Black	9			12.7
White	51			71.8
>1	4			5.6
Unknown	6			8.5
Ethnicity
Not Hispanic/ Latino	60			84.5
Hispanic/Latino	11			15.5
Years of education	62			16.7 ± 2.85
Cognitive Measures
Assessment	n			Mean ± SD or %
Stroop Interference	69			44.6 ± 9.18
Initiation/Perseveration subscale of Dementia Rating Scale	71			35.4 ± 3.15
Digit Symbol (WAIS-III)	71			41.6 ± 9.53
Logical Memory (WMS-R) delayed raw score	71			13.1 ± 4.35
Depression Measures
Characteristic	Baseline		Post treatment		Post-pre treatment difference
	n	Mean ± SD or %	n	Mean ± SD or %	p-valuea(t-statistic)
24-item Hamilton Rating Scale for Depression	71	20.3 ± 6.53	68	13.5 ± 7.93	<.001 (−6.65)
Quick Inventory of Depressive Symptomatology Self Report	71	10.8 ± 4.26	67	6.75 ± 4.95	<.001 (−6.33)
Clinical Global Impressions—Severity	71	3.9 ± 0.74	67	2.9 ± 1.42	<.001 (−6.47)
Response and Remission Rates
Characteristic	n			%
Response rates (≥ 50% decrease in 24-item Hamilton Rating Scale for Depression at post-treatment)	24/68			35.3
Remission rates (≤ 7 24-Hamilton Rating Scale for Depression at post-treatment)	20/68			29.4
Clinical Global Impressions—Improvement (score of 1 or 2 at post-treatment)	31/67			46.3
Medication
Medication	n			%
Escitalopram	28/71			39.4
Duloxetine	43/71			60.6

^aPaired t-test; df = 67, 66, 66 for 24-item Hamilton Rating Scale for Depression, Quick Inventory of Depressive Symptomatology Self Report, and Clinical Global Impressions-Severity, respectively. The df differ by measure due to the differing number of missing values for each depression measure that was evaluated.

Abbreviations: WAIS-III: Wechsler Adult Intelligence Scale-III, WMS-R: Wechsler Memory Scale-Revised, SD: standard deviation, df: degrees of freedom.