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. 2021 Jul 22;11:14977. doi: 10.1038/s41598-021-93828-y

Table 1.

Demographic and clinical characteristics of health-care workers (HCWs) exhibiting a negative or a positive RT-PCR test for SARS-CoV-2.

Negative SARS-CoV-2 HCWs (n = 252) Positive SARS-CoV-2 HCWs (n = 67) p-value Adjusted p-value
Male sex. n (%) 50 (19.84) 9 (13.43) 0.306 0.638
Age. years. median [IQR] 35.9 [27.5–47.0] 36.0 [29.4–47.7] 0.656 0.926
Body Mass Index*. n 249 67
median [IQR] 23.3 [21.1–27.1] 24 [22.5–27.3] 0.148 0.473
Currently smoker. n (%) 64/252 (25.4) 6/67 (8.96) 0.013 0.091
Alcohol consumption*. Daily. n(%) 8/251 (3.19) 3/67 (4.48) 0.248 0.606
Presence of comorbidity*. n (%) 109/249 (43.78) 17/66 (25.76) 0.012 0.091
Description of comorbidity
Neurological disorders. n (%) 7 (6.42) 1 (5.88) 1.000 1.000
Cardiovascular disorders. n (%) 2 (1.83) 1 (5.88) 0.355 0.649
Hypertension. n (%) 14 (12.84) 3 (17.65) 0.701 0.935
Heart Failure. n (%) 3 (2.75) 1 (5.88) 0.444 0.735
Diabetes. n (%) 5 (4.59) 0 (0) 1.000 1.000
Immune deficiency. n (%) 2 (1.83) 0 (0) 1.000 1.000
Liver disease. n (%) 2 (1.83) 0 (0) 1.000 1.000
Kidney disease. n (%) 1 (0.92) 1 (5.88) 0.253 0.606
Cancer. n (%) 2 (1.83) 1 (5.88) 0.355 0.649
Hypothyroidy. n (%) 11 (10.09) 2 (11.76) 0.688 0.935
Rheumatic disease. n (%) 2 (1.83) 2 (11.76) 0.088 0.324
Chronic respiratory disease. n (%) 25 (22.94) 1 (5.88) 0.193 0.580
HCW in contact with patients. n (%) 228/252 (90.48) 64/67 (95.52) 0.284 0.634
Delay from symptoms to screening. day. median [IQR] 5 [3–8] 3 [2–6] 0.015 0.091
Symptom
Fever. n (%) 149/252 (59.13) 45/67 (67.16) 0.291 0.634
Sore throat*. n (%) 55/250 (22) 12/67 (17.91) 0.576 0.837
Diarrheas. n (%) 104/252 (41.27) 16/67 (23.88) 0.014 0.091
Pain. n (%) 187/252 (74.21) 53/67 (79.1) 0.505 0.758
Muscular. n (%) 155 (82.89) 50 (94.34) 0.062 0.249
Chest. n (%) 38 (20.32) 11 (20.75) 1.000 1.000
Joints. n (%) 24 (12.83) 3 (5.66) 0.225 0.601
Abdominal. n (%) 72 (38.5) 12 (22.64) 0.048 0.232
Asthenia*. n (%) 204/250 (81.6) 56/67 (83.58) 0.845 1.000
Rhinorrhea *. n (%) 121/250 (48.4) 46/67 (68.66) 0.005 0.079
Nauseas*. n (%) 68/249 (27.31) 14/67 (20.9) 0.365 0.649
Cough. n (%) 135 (53.57) 47 (70.15) 0.022 0.115
Shortness of breath*. n (%) 96/249 (38.55) 21/67 (31.34) 0.346 0.649
Headaches. n (%) 198 (78.57) 54 (80.6) 0.847 1.000
Irritability*. n (%) 65/250 (26) 14/67 (20.9) 0.485 0.758
Anosmia. n (%) 24 (9.52) 26 (38.81)  < 0.001  < 0.001
Ageusia. n (%) 27 (10.71) 25 (37.31)  < 0.001  < 0.001
Ophthalmic pain. n (%) 28 (11.11) 6 (8.96) 0.775 0.979
Hospitalized. n (%) 0/252 (0) 2/67 (2.98) 0.043 0.187

*Missing data.