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. 2021 Jul 22;11:15047. doi: 10.1038/s41598-021-94377-0

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Autoantibody profile in patients. The antibody array depicts the positive autoantibodies against the corresponding proteins (blue boxes), negative results are shown as grey boxes and white boxes indicate that the test was not assigned. The colored line under the antibody names described the retina proteins (dark blue), glycolytic enzymes (yellow), and unidentified retina proteins (grey). The last column on the right describes the total number of antibodies in each patient (green gradient) and the lowest row shows the number of patients having each type of antibody (red gradient). (b) Prevalence of autoantibodies in 44 patients. Bar chart depicts the prevalence of the autoantibodies based on the three protein panels: retina proteins (dark blue), glycolytic enzyme (yellow), and unidentified retina proteins (grey). HSP heat shock protein, CAII carbonic anhydrase II, TULP1 tubby-like protein 1, CRMP collapsin response mediator protein, GAPDH glyceraldehyde 3-phosphate dehydrogenase, PKM2 pyruvate kinase isozyme M2, kDa kilo Dalton.