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CS-semi5 attenuates CIA-induced arthritis in vivo. (A) Histologic sections of ankle joints following immunostaining with MCP-1 and NF‐κB antibodies (40×magnification). (B) Positive staining was measured by digital quantification. (C,D) Serum IL-1β and TNF‐α were assessed by ELISA. n = 7. ## p < 0.01 compared with Control group; *p < 0.05 and **p < 0.01 compared with Model group.
