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. 2020 Feb 26;3:100046. doi: 10.1016/j.prdoa.2020.100046

Table 2.

Prevalence of clinical indicators of advanced Parkinson's disease, by assigned disease severity groupa, b.

Indicator Overall
(N = 144,703)
Mild-Moderate PD (n = 115,729)
Advanced PD
(n = 28,974)
N Percent N Percent N Percent
Any deep brain stimulationc 3690 2.6% 1880 1.6% 1810 6.2%
Fall 8099 5.6% 6298 5.4% 1801 6.2%
Hallucinations 4724 3.3% 3246 2.8% 1478 5.1%
Walker 7907 5.5% 6250 5.4% 1657 5.7%
Wheelchair 12,784 8.8% 9739 8.4% 3045 10.5%
Specialty bed 7711 5.3% 5974 5.2% 1737 6.0%
Dementia 55,085 38.1% 45,347 39.2% 9738 33.6%
Skilled nursing facility 374 0.3% 267 0.2% 107 0.4%
Hospice 2545 1.8% 1913 1.7% 632 2.2%

PD, Parkinson's disease.

a

Patients were classified based on an algorithm derived from prescription claims. Patients with any 30-day average levodopa equivalent dose (LED) >1000 mg/day were classified as advanced; all others were classified as mild-moderate.

b

Comparisons of patient subgroups for all variables listed were statistically significant at the P < 0.001 level.

c

Deep brain stimulation was defined as the presence of any CPT code indicating current or recent treatment (e.g., device placement or programming).