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. 2021 Jul 9;8:686053. doi: 10.3389/fnut.2021.686053

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Copyright © 2021 Wang, Hu, Tang, Azad, Zhu, He and Kong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of maternal probiotic or synbiotic supplementation on the intestinal morphology of offspring piglets. Histomorphology of the jejunum and ileum was observed by light microscopy after H&E staining. (A) The images of the jejunum and ileum morphology at 40 × and 100 × magnification were shown, respectively. (B) Statistical analysis of villus height (VH), (C) crypt depth (CD), and (D) the ratio of VH to CD. Data are represented as means ± SEM, n = 8 per group. Different letters indicate significant differences among the groups (P < 0.05). C, control group; A, antibiotic group; P, probiotic group; and S, synbiotic group.