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. 2021 Jul 9;8:690521. doi: 10.3389/fcvm.2021.690521

Table 4.

Association of asymptomatic cardiovascular impairments with individual components of MS.

Variables LVH LV diastolic dysfunction Arteriosclerosis Microalbuminuria
Model 1 Model 2 Model 1 Model 2 Model 1 Model 2 Model 1 Model 2
OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
Central obesity 1.866 (1.451–2.400) <0.001 1.750 (1.354–2.262) <0.001 1.730 (1.230–2.433) 0.002 1.543 (1.091–2.182) 0.014 1.751 (1.234–2.483) 0.002 1.468 (1.025–2.102) 0.036 1.393 (1.151–1.687) 0.001 1.257 (1.032–1.532) 0.031
High BP 1.734 (1.310–2.294) <0.001 1.577 (1.185–2.099) 0.002 1.968 (1.320–2.935) 0.001 1.744 (1.162–2.617) 0.007 3.241 (1.953–5.379) <0.001 2.853 (1.702–4.783) <0.001 1.490 (1.210-−1.835) <0.001 1.340 (1.082–1.661) 0.007
Elevated PG 1.158 (0.917–1.462) 0.217 1.055 (0.830–1.340) 0.661 1.453 (1.073–1.969) 0.016 1.306 (0.957–1.783) 0.092 2.711 (1.965–3.741) <0.001 2.561 (1.838–3.569) <0.001 1.524 (1.261–1.842) <0.001 1.419 (1.169–1.722) <0.001
High TG 1.096 (0.869–1.383) 0.4401 1.023 (0.781–1.340) 0.867 1.463 (1.078–1.987) 0.015 1.414 (0.994–2.012) 0.054 1.345 (0.974–1.855) 0.072 1.289 (0.892–1.863) 0.177 1.351 (1.120–1.630) 0.002 1.293 (1.040–1.608) 0.021
Low HDL-c 1.048 (0.828–1.327) 0.697 0.949 (0.722–1.248) 0.710 1.115 (0.818–1.520) 0.490 0.853 (0.597–1.219) 0.382 0.909 (0.649–1.274) 0.579 0.685 (0.467–1.018) 0.063 1.130 (0.933–1.368) 0.212 0.913 (0.731–1.141) 0.425

The ORs and 95% CI were calculated to estimate the associations of various cardiovascular impairments with individual components of MS by using binary logistic regression models. Model 1 was adjusted for age, sex, serum creatinine, serum uric acid, smoking status, and family history of premature CVD. Model 2 was further adjusted for the other four MS components simultaneously.

BP, blood pressure; CI, confidence interval; CVD, cardiovascular diseases; HDL-c, high-density lipoprotein cholesterol; LV, left ventricle; LVH, left ventricle hypertrophy; MS, metabolic syndrome; OR, odds ratio; PG, plasma glucose; TG, triglyceride.