Table 4. Results of the Linear Mixed Effect Model for Regional Cortical Thickness and Hippocampal Volume.
Cortical region | Group effect | Time effect | Group×time | |||
---|---|---|---|---|---|---|
β (95% CI) | p value | β (95% CI) | p value | β (95% CI) | p value | |
Lt. cingulate thickness | −0.06 (−0.17, 0.04) | 0.233 | −0.03 (−0.06, −0.002) | 0.036 | 0.02 (−0.04, 0.07) | 0.601 |
Rt. cingulate thickness | 0.01 (−0.08, 0.10) | 0.789 | −0.05 (−0.07, −0.02) | <0.001 | 0.01 (−0.03, 0.06) | 0.544 |
Lt. frontal thickness | −0.04 (−0.11, 0.02) | 0.198 | −0.04 (−0.06, −0.02) | <0.001 | 0.001 (−0.04, 0.04) | 0.943 |
Rt. frontal thickness | −0.02 (−0.08, 0.04) | 0.491 | −0.04 (−0.06, −0.02) | <0.001 | 0.01 (−0.02, 0.05) | 0.399 |
Lt. parietal thickness | −0.04 (−0.14, 0.05) | 0.376 | −0.06 (−0.08, −0.03) | <0.001 | 0.01 (−0.04, 0.06) | 0.581 |
Rt. parietal thickness | −0.01 (−0.10, 0.08) | 0.859 | −0.05 (−0.06, −0.03) | <0.001 | −0.005 (−0.04, 0.03) | 0.782 |
Lt. temporal thickness | −0.05 (−0.14, 0.04) | 0.260 | −0.07 (−0.09, −0.04) | <0.001 | −0.000008 (−0.05, 0.05) | 0.999 |
Rt. temporal thickness | −0.03 (−0.12, 0.06) | 0.532 | −0.06 (−0.08, −0.04) | <0.001 | 0.01 (−0.04, 0.05) | 0.664 |
Lt. occipital thickness | −0.003 (−0.11, 0.10) | 0.954 | −0.07 (−0.10, −0.04) | <0.001 | 0.02 (−0.04, 0.08) | 0.546 |
Rt. occipital thickness | 0.01 (−0.08, 0.11) | 0.778 | −0.05 (−0.07, −0.03) | <0.001 | 0.02 (−0.02, 0.07) | 0.309 |
Lt. hippocampal volume | 42.72 (−275.9, 361.4) | 0.788 | −116.39 (−200.6, −32.2) | 0.008 | 43.30 (−126.0, 212.6) | 0.609 |
Rt. hippocampal volume | −12.77 (−344.7, 319.2) | 0.939 | −111.22 (−201.3, −21.1) | 0.017 | 61.50 (−119.1, 242.1) | 0.496 |
β, beta coefficient; CI, confidence interval; Lt, left; Rt, right.
The terms for time were defined as 0 for baseline and 1 for 12-month follow-up.