Table 6. Associations for REU Score with Cytokines and Metal Ions by Multiple Linear Regression Analysis.
| Unstandardized coefficients | Standardized coefficients | t | p value | Collinearity statistics | ||||
|---|---|---|---|---|---|---|---|---|
| B | SE | β | Tolerance | VIF | ||||
| Constant | 4.680 | 0.564 | 8.300 | <0.001† | ||||
| IL-6 | 0.024 | 0.005 | 0.457 | 5.106 | <0.001† | 0.981 | 1.019 | |
| Ni | 0.057 | 0.027 | 0.190 | 2.126 | 0.036* | 0.981 | 1.019 | |
Variables: Ti, titanium; Cr, chromium; Co, cobalt; Ni, nickel; Zr, zirconium; Pd, palladium; Ag, silver; Pt, platinum; Au, gold; IL, interleukin; TNF, tumor necrosis factor; dependent variable: REU, reticulation/keratosis, erythema, and ulceration score; B, regression coefficient; SE, standard error; β, standardized coefficient; VIF, variation inflation factor.
R2 (0.269), adjusted R2 (0.253), F=17.100, p=0.000, Durbin-Watson (1.925). A stepwise regression method was utilized. A multiple regression analysis was performed in the OLL group.
*p<0.05, †p<0.001.