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. 2021 Jul 9;12:539835. doi: 10.3389/fpsyt.2021.539835

Table 3.

Symptoms and signs from DSM-5 diagnostic criteria.

Female ASD Male ASD p-value
N % N %
(A1) Deficit in social-emotional reciprocity
Abnormal social approach 34 62.96 39 70.9 0.34363
Failure of normal back-and-forth conversation 44 81.4 48 87.2 0.2999
Reduced sharing of interests, emotions, or affect 41 75.9 41 74.5 0.7999
Failure to initiate or respond to social interaction 36 66.6 36 65.4 0.7372
(A2) Deficit in non-verbal communicative behaviors used for social interaction
Poorly integrated verbal and non-verbal communication 39 72.2 30 54.5 0.9765
Abnormalities in eye contact and body language 42 77.77 45 81.8 0.2923
Deficits in understanding and use of gestures 28 51.8 34 61.8 0.2409
A total lack of facial expressions and nonverbal communication 7 12.96 14 25.45 0.1203
(A3) Deficits in developing, maintaining, and understanding relationships
Difficulties adjusting behavior to suit various social contexts 33 61.1 47 85.4 0.0084
Difficulties in sharing imaginative play 29 53.7 42 76.3 0.0476
Difficulties in making friends 52 96.29 53 96.36 0.6463
Absence of interest in peers 6 11.11 7 12.7 0.5893
(B1) Stereotyped or repetitive motor movements, use of objects, or speech
Simple motor stereotypies, lining up toys, or flipping objects 33 61.1 33 60 0.5456
Echolalia, idiosyncratic phrases 18 33.33 16 29.09 0.8505
(B2) Insistence on sameness, inflexible adherence to routines, or ritualized patterns or verbal non-verbal behavior
Extreme distress at small changes and/or difficulties with transitions 36 66.66 44 80 0.1065
Rigid thinking patterns. greeting rituals 30 55.55 41 74.54 0.0303
Need to take the same route or eat food every day 29 53.7 25 45.45 0.8808
(B3) Highly restricted. fixated interests that are abnormal in intensity or focus
Strong attachment to or preoccupation with unusual objects 15 27.77 16 29.09 0.5899
Excessively circumscribed or perseverative interest 48 88.8 52 94.54 0.1897
(B4) Hyper- or hyporeactivity to sensory input or unusual interests in sensory aspects of the environment
Apparent indifference to pain/temperature 2 3.7 1 1.81 0.8988
Adverse response to specific sounds or textures 36 66.66 41 74.54 0.4451
Excessive smelling or touching of objects 23 42.59 11 20 0.9945
Visual fascination with lights or movement 3 5.55 12 21.81 0.0209

ASD, autism spectrum disorder.