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. 2021 Jul 9;8:676554. doi: 10.3389/fmed.2021.676554

Table 2.

Overall (A) and c3 of (B) vessel density of deep capillary plexus (DCP) of patientspost−COVID who were hospitalized and non-hospitalized during COVID-19 infection: (A) mixed model analysis showed a significantly reduced overall LS-mean vessel density (VD) for hospitalized (coded as 1) compared with non-hospitalized patients (coded as 0); (B) general linear model (non-hospitalized, hospitalized patientspost−COVID and controls) showed a significantly reduced VD of c3 of DCP for hospitalized < non-hospitalized < controls.

(A)
Type 3 tests of fixed effects of vessel density of DCP
Effect Num DF Den DF F value Pr > F
Hospitalized 1 29 5.18 0.0304
Gender 1 29 2.58 0.1188
Age 1 29 0.06 0.8099
Sector 11 352 2.92 0.001
Least squares means of vessel density of DCP
Effect Groups Estimate Standard error DF t Pr > |t| Alpha Lower Upper
Hospitalized 0 24.23 0.8928 29 27.14 <0.0001 0.05 22.404 26.06
Hospitalized 1 21.003 0.9006 29 23.32 <0.0001 0.05 19.161 22.85
Differences of least squares means of vessel density of DCP
Effect Group Group Estimate Standard Err. DF t Value Pr > |t| Adj p Alpha Lower Upper Adj lower Adj Upper
Hospitalized 0 1 3.23 1.42 29 2.28 0.03 0.03 0.05 0.33 6.13 0.33 6.13
(B)
Least squares means of c3 of DCP for effect groups
t for H0: LS-mean(i) = LS-mean(j)/Pr > |t|
Dependent Variable: c3 of DCP
i/j Non-hospitalized Hospitalized Control
Non-hospitalized 2.822824 0.124304
0.0178 0.9915
Hospitalized −2.82282 −2.72584
0.0178 0.0229
Control −0.1243 2.725835
0.9915 0.0229