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. 2021 Jul 9;22(3):653. doi: 10.3892/ol.2021.12914

Figure 6.

Figure 6.

Analysis of the prognostic value of the 10 hub genes in HCC using Kaplan-Meier Plotter. The 10 hub genes were represented by hazard ratios with a 95% confidence interval. AURKA [HR=1.9 (1.33–2.71), log-rank P=3.6×10−4], BIRC5 [HR=2.56 (1.79–3.66), log-rank P=8.6×10−8, BUB1B [HR=2.07 (1.45–2.97), log-rank P=4.7×10−5], CCNA2 [HR=2.76 (1.65–4.62), log-rank P=5.5×10−5], CCNB1 [HR=2.72 (1.74–4.26), log-rank P= 5.1×10−6], CCNB2 [HR=2.2 (1.42–3.39), log-rank P=2.7×10−4], CDC20 [HR=2.8 (1.9–4.13), log-rank P= 5.7×10−8], CDK1 [HR=2.2 (1.53–3.16), log-rank P=1.2×10−5], DLGAP5 [HR=2.83 (1.77–4.54), log-rank P=6.4×10−6] and MAD2L1 [HR=2.47 (1.65–3.7), log-rank P=5.3×10−6] High expression levels of AURKA, BIRC5, BUB1B, CCNA2, CCNB1, CCNB2, CDC20, CDK1, DLGAP5 and MAD2L1 were associated with poor overall survival. Log-rank P<0.05 was considered to indicate a statistically significant difference. HR, hazard ratio.