FIGURE 8.

The Proposed impact of the MM500 study data under the clinical treatment cycle, where the patient from a healthy state enters into a progressive disease evolvement process. The first indication of early melanoma disease onset is discovered by an image capture, for example, CT (high resolution), and/or MR, accompanied by a genomic mutation signature, along with protein localization and expression. Assignments of posttranslational modifications, as well as pathway biology activations, and histopathology characterizations added to the disease status. Based on the diagnosis output, a dedicated and optimized drug treatment is presented to the patient. The melanoma disease cycle is reinforced upon metastasis development, that entails a resistance build up