TABLE 3.

Studies reporting increased level of caspase-9 in retinal disease.

Disease (n)	Controls (n)	Casp9 Measured	Detection Method	Tissue Examined	Pathological Casp9 Localization	Ref.
RD (4)	Normal (10)	Unspecified cl-casp9	IHC	Retina (postmortem)	Photoreceptors	Hisatomi et al. (2008)
RRD (33)	--	D315 cl-casp9	Immunoassay	Subretinal fluid	--	Carpineto et al. (2016)
T2D (10)	Normal (10)	Unspecified cl-casp9	IHC	Retina (postmortem)	Ganglion cell layer	Oshitari et al. (2008)
Glaucoma (10–38)	Normal (10–30)	Unspecified cl-casp9	LC-MS/MS, Western blot, IHC	Retina (postmortem)	Ganglion cells	Yang et al. (2011)

RD, Retinal detachment; RRD, rhegmatogenous retinal detachment; T2D, Type 2 diabetes.