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. 2020 Apr 13;2:92–99. doi: 10.1016/j.xjtc.2020.04.001

Table 7.

Receiver operating characteristic analysis for the 5 intraoperative negative predictive value (NPV) of hyperlactatemia

Factor AUC 95% confidence interval P value Cutoff value Sensitivity, % Specificity, % NPV, %
High DO2i on CPB 0.75 0.70-0.83 .001 299 mL/min/m2 73 74 77
Low O2ERi on CPB 0.79 0.73-0.85 .001 24% 73 76 79
Low blood glucose on CPB 0.89 0.82-0.93 .001 128 mg/dL 79 80 74
High CI on CPB 0.68 0.65-0.79 .039 2.4 L/min/m2 64 69 63
High SvO2 on CPB 0.63 0.60-0.78 .035 85% 62 67 62

AUC, Area under the curve; NPV, negative predictive value; DO2i, indexed oxygen delivery; CPB, cardiopulmonary bypass; O2ERi, indexed oxygen extraction ratio; CI, cardiac index; SvO2, mixed venous oxygen saturation.