Table 1.
Summary of Pertinent Patient Metadata for the 12,476 Unique Patients
| Variable | B.1.1.7 variant | Other variants | Total | Statistical analysis |
|---|---|---|---|---|
| Patients with data | 3276 (26.3) | 9200 (73.7) | 12,476 | |
| Patient characteristics | ||||
| Median age, years | 49.9 | 53.7 | 52.5 |
P < 0.0001 (U-test) |
| Female sex | 1693 (51.7) | 4880 (53.0) | 6573 (52.7) |
P = 0.1854 (Fisher exact test) |
| Male sex | 1583 (48.3) | 4320 (47.0) | 5903 (47.3) | |
| Race/ethnicity | ||||
| White | 1304 (40.1) | 3720 (40.6) | 5024 (40.5) |
P < 0.0001 (χ2 test) |
| Hispanic or Latino | 945 (29.1) | 2720 (29.7) | 3665 (29.5) | |
| Black | 748 (23.0) | 1644 (18.0) | 2392 (19.3) | |
| Asian | 128 (3.9) | 549 (6.0) | 677 (5.5) | |
| Native American | 16 (0.5) | 28 (0.3) | 44 (0.4) | |
| Hawaiian/Pacific Islander | 3 (0.1) | 23 (0.3) | 26 (0.2) | |
| Unavailable | 107 (3.3) | 472 (5.2) | 579 (4.7) | |
| BMI, kg/m2 | ||||
| Median | 30.4 | 29.5 | n = 11,009 |
P < 0.0001 (U-test) |
| <18.5 | 48 (1.5) | 140 (1.5) | 188 (1.5) |
P < 0.0001 (χ2 test) |
| 18.5–25 | 506 (15.4) | 1608 (17.5) | 2114 (16.9) | |
| 25–30 | 857 (26.2) | 2520 (27.4) | 3377 (27.1) | |
| 30–35 | 740 (22.6) | 1833 (19.9) | 2573 (20.6) | |
| ≥35 | 811 (24.8) | 1946 (21.2) | 2757 (22.1) | |
| Unknown | 314 (9.6) | 1153 (12.5) | 1467 (11.8) | |
| Admission data | ||||
| Admitted | 1768 (54.0) | 4265 (46.4) | 6033 (48.4) |
P < 0.0001 (Fisher exact test) Odds ratio: 1.357 (95% CI, 1.252–1.469) |
| Not admitted | 1508 (46.0) | 4935 (53.6) | 6443 (51.6) | |
| Median LOS, days | 5.1 | 5.2 | 5.2 |
P = 0.8917 (U-test) |
| Maximum respiratory support | ||||
| ECMO | 8 (0.5) | 17 (0.4) | 25 (0.4) |
P = 0.0135 (χ2 test) |
| Mechanical ventilation | 150 (8.5) | 365 (8.6) | 515 (8.5) | |
| Noninvasive ventilation | 169 (9.6) | 433 (10.2) | 602 (10.0) | |
| High-flow oxygen | 358 (20.2) | 696 (16.3) | 1054 (17.5) | |
| Low-flow oxygen | 734 (41.5) | 1830 (42.9) | 2564 (42.5) | |
| Room air | 349 (19.7) | 924 (21.7) | 1273 (21.1) | |
| Mortality | ||||
| Alive | 3132 (95.6) | 8760 (95.2) | 11,892 (95.3) |
P = 0.3862 (Fisher exact test) Odds ratio: 0.915 (95% CI, 0.755–1.111) |
| Deceased | 144 (4.4) | 440 (4.8) | 584 (4.7) | |
| Median PCR CT | ||||
| Abbott Alinity | 23.9 (n = 1133) | 26.8 (n = 3344) | n = 4477 |
P < 0.0001 (U-test) |
| Hologic Panther | 25.0 (n = 385) | 26.2 (n = 1574) | n = 1959 |
P = 0.0274 (U-test) |
| Vaccine | ||||
| No vaccine | 3023 (92.3) | 8715 (94.7) | 11,738 (94.1) |
P < 0.0001 (χ2 test) |
| >7 Days past first vaccine | 127 (3.9) | 404 (4.4) | 531 (4.3) | |
| >14 Days past second vaccine | 126 (3.8) | 81 (0.9) | 207 (1.7) | |
Data are given as n (%), unless otherwise indicated. Data include 12,476 unique patients with high-quality sequence results between January 1, 2021, and May 31, 2021.
BMI, body mass index; ECMO, extracorporeal membrane oxygenation; LOS, length of stay.