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. 2021 Sep 2;184(18):4713–4733.e22. doi: 10.1016/j.cell.2021.07.023

Table 1.

Participant characteristics

Control (WHO score 0) Intubated control (WHO score 7–8) COVID-19 m/m (WHO score 1–5) COVID-19 severe (WHO score 6–8) COVID-19 conv. (WHO score 0)
Case number 25.9% (15/58) 10.3% (6/58) 24.1% (14/58) 36.2 (21/58) 3.4% (2/58)

Age (years)

Minimum 27 33 19 28 20
Median (IQR) 58 (16) 65.5 (31) 49.5 (17.8) 62 (13) N/A
Maximum 73 71 69 84 57

Sex

Female 60% (9/15) 16.7% (1/6) 42.9% (6/14) 47.6% (10/21) 50% (1/2)
Male 40% (6/15) 83.3% (5/6) 57.1% (8/14) 52.4% (11/21) 50% (1/2)

Ethnicity

Hispanic 0% (0/15) 0% (0/6) 0% (0/14) 4.8% (1/21) 0% (0/2)
Not Hispanic 100% (15/15) 100% (6/6) 100% (14/14) 95.2% (20/21) 100% (2/2)

Race

Black/African American 66.7% (10/15) 66.7% (4/6) 71.4% (10/14) 61.9% (13/21) 50% (1/2)
White 33.3% (5/15) 33.3% (2/6) 28.6% (4/14) 23.8% (5/21) 50% (1/2)
American Indian 0% (0/15) 0% (0/6) 0% (0/14) 14.3% (3/21) 0% (0/2)

BMI

Median (IQR) 37.5 (14.4) 30.5 (18.1) 23.0 (11.6) 31.9 (14.2) 40.7

Pre-existing conditions

Diabetes 40% (6/15) 33.3% (2/6) 28.6% (4/14) 71.4% (15/21) 0% (0/2)
Chronic kidney disease 6.7% (1/15) 0% (0/6) 7.1% (1/14) 19.0% (4/21) 0% (0/2)
Congestive heart failure 6.7% (1/15) 16.7% (1/6) 0% (0/14) 4.8% (1/21) 0% (0/2)
Lung disorder 6.7% (1/15) 16.7% (1/6) 28.6% (4/14) 38.1% (8/21) 0% (0/2)
Hypertension 86.7% (13/15) 50% (3/6) 42.9% (6/14) 81.0% (17/21) 0% (0/2)
IBD 13.3% (2/15) 0% (0/6) 0% (0/14) 0% (0/21) 50% (1/2)

Treatment

Corticosteroids N/A 33.3% (2/6) 42.9% (6/14) 66.7% (14/21) N/A
Remdesivir N/A 0% (0/6) 14.3% (2/14) 4.8% (1/21) N/A
28-day mortality ∗∗∗ 0% (0/15) 33.3% (2/6) 0% (0/14) 76.2% (16/21) 0% (0/2)

Continuous variables were compared by Kruskal-Wallis test. Categorical variables were compared by chi-square test. ∗∗∗p < 0.001, p < 0.05, otherwise non-significant. m/m, mild/moderate; conv, convalescent; IQR, inter-quartile range; BMI, body mass index; IBD, inflammatory bowel disease.