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. 2021 Jul 23;184(19):4969–4980.e15. doi: 10.1016/j.cell.2021.07.025

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Figure S4 — Neutralization profiles for monoclonal antibodies of seven clusters, related to Figure 4

(A) Authentic virus (WA1) neutralization profiles of 9 antibodies. (B) Pseudovirus neutralization profiles in two cell lines for antibodies from NTD-1 cluster. Left panel: neutralization profiles in 293FT cells co-expressing hACE2 and TMPRSS2 as target cells (n = 39). Right panel: neutralization profiles in TZM.bl cells expressing hACE2 as target cells (n = 13). (C) Pseudovirus neutralization profiles in 293FT cells co-expressing hACE2 and TMPRSS2 for antibodies from RBD-1 (n = 22), RBD-2 (n = 23), RBD-3 (n = 5), NTD-2 (n = 16), S2-1 (n = 32) and S2-2 (n = 19) clusters. Data are mean values ± SD for authentic virus assays and pseudovirus assays using 293FT/hACE2/TMPRSS2 cells. Data are mean values ± SEM for assays using TZM.bl/hACE2 cells.