Table 2c.
Risk factor assessment of individual immunosuppressive drugs regarding humoral vaccination failure at T2 based on logistic regression.
| IS class | OR | Wald CI | p-value | |
|---|---|---|---|---|
| Steroids | No | Ref | ||
| Yes | 1.374 | [0.885; 2.132] | 0.157 | |
| CNI | No | Ref | ||
| Yes | 3.604 | [1.798; 7.222] | <0.001 | |
| MMF/MPA | No | Ref | ||
| Yes | 3.7938 | [2.243; 6.430] | <0.001 | |
| mTORi | No | Ref | ||
| Yes | 1.935 | [0.968; 3.869] | 0.062 | |
| Belatacept | No | Ref. | ||
| Yes | 7.085 | [1.973; 25.446] | 0.003 | |
IS means immunosuppression; Steroids = glucocorticosteroids; CNI = calcineurin-inhibitor; MMF-MPA = mycophenolate mofetil or mycophenolic acid; mTOR-I = mTOR-inhibitors; T2 = 8 weeks after first vaccination.