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. 2021 Jul 23;101(3):115507. doi: 10.1016/j.diagmicrobio.2021.115507

Table 3.

Bacteriological results according to the type of respiratory samples

Samples (n = 119)
ETA (n = 74) BAL (n = 45)
Type of pneumonia
 CAP: suspected/confirmed
 VAP: suspected/confirmed
15 / 5
59 / 34
12 / 1
33 / 14
Antibiotics 48h prior to samples (n = 55) 32 (58) 23 (42)
Positive direct examination
 Presence of Gram +
 Presence of Gram –
 Polymicrobial		 39 (53)
6 (15)
9 (23)
24 (62)		 14 (33)
3 (21)
1 (7)
10 (72)
Infection polymicrobial
  FAPP (n = 18)
 Mean number of bacteria detected
  CC (n = 8)
 Mean number of bacteria detected
14 (77)
2.2
5 (62)
2.2
4 (23)
2.25
3 (38)
2
Bacterial copathogens:
  Staphylococcus aureus
 Pseudomonas aeruginosa
 Haemophilus influenzae
 Escherichia coli
 Klebsiella pneumoniae
 Enterobacter cloacae
 Klebsiella aerogenes
 Proteus spp.
  Serratia marcescens
 Streptococcus agalactiae
 Moraxella catarrhalis
 Mycoplasma pneumoniae
 Morganella morganii
 Hafnia alvei
 Providencia stuartii 		FAPP / CC
12 / 6
10/ 10
7 / 2
7 / 4
6 / 6
3 / 3
3 / 1
4 / 3
2 / 2
2 / 1
2 / 1
1 / NA
NA / 1
NA / 1a
NA / 1a 		FAPP / CC
5 / 6
1 / 1
3 / 1
2 / 1
1 / 1
2 / 2
1 / 1
0 / 0
1 / 1
1 / 0
0 / 0
0 / NA
NA / 1
NA / 0
NA / 0
Resistance detection:
 MRSA
 3GC-R Gram-negative bacillib 		FAPP / AST
5 / 0
4 / 3		 FAPP / AST
1 / 0
1 / 3

Data are presented as: n (%).

ETA = endotracheal aspirate; BAL = bronchoalveolar lavage; CAP = community-acquired pneumonia (defined as infections occurring during the first 48h of ICU admission); VAP = ventilator-associated pneumonia; FAPP = FilmArray Pneumonia Panel; CC = conventional culture; AST = antimicrobial susceptibility testing; MRSA = methicillin-resistant S. aureus; 3GC-R = third generation cephalosporins resistance; NA = not applicable (species not detected either by the FAPP or by the CC).

a The isolation of H. alvei and P. stuartii in CC had no impact on antibiotic therapy as they were covered by the antibiotics administered following the detection of other pathogens detected by FAPP.

b Among 3GC-resistant Gram-negative bacilli, 3 CTX-M were detected by both FAPP and CC, 2 CTX-M were detected only by FAPP, 2 ESBL not belonging to CTX-M as well as one 3GC-resistant P. aeruginosa were detected only by CC.