Table 2. Clinical Outcomes Among Overall Population by Receipt of Bone Resorption Inhibitors.

Outcome	Abiraterone acetate cohort (n = 529)	BRI cohort (n = 216)	HR (95% CI)	P value
Deaths, No.	369	147	NA	NA
OS, median (95% CI), mo	23.0 (21.0-25.7)	31.8 (28.2-36.4)	0.65 (0.54-0.79)	<.001
SREs, No.	188	116	NA	NA
Time to first SRE, median (95% CI), mo	42.7 (33.2-52.2)	32.4 (24.1-37.3)	1.27 (1.0-1.60)	.04

Abbreviations: BRI, bone resorption inhibitor; HR, hazard ratio; NA, not applicable; OS, overall survival; SRE, skeletal-related event.