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Brunt system for staging NASH fibrosis (from Brunt et al., 1999) 33.
| Stage | Zone 3, Sinusoidal | Portal Based | Bridging | Cirrhosis |
|---|---|---|---|---|
| 1 | Focal or extensive | 0 | 0 | 0 |
| 2 | Focal or extensive | Focal or extensive | 0 | 0 |
| 3 | Bridging septa | Bridging septa | + | 0 |
| 4 | ± | ± | Extensive | + |
Evaluation of fibrosis is performed by Masson trichrome histochemical stain.
