Table IV.
Paris criteria for PBC-AIH variant diagnosis.
At least 2 out of 3 criteria for each disease | |
---|---|
Primary biliary cholangitis | Autoimmune hepatitis |
ALP > 2x ULN or γGT > 5x ULN | ALT > 5x ULN |
AMA > 1:40 | IgG serum levels > 2x ULN or ASMA positivity |
Florid duct lesions on histology | Moderate or severe IH on histology |
ALP: alkaline phosphatase; ULN: upper limit of normal; γGT: γ-glutamyltranspeptidase; AMA: anti-mitochondrial antibodies; ALT: alanine aminotransferase; ASMA: anti-smooth muscle antibodies; IH: interface hepatitis.