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. 2021 Jul 20;13(3):328–334. doi: 10.3390/neurolint13030033

Table 1.

Diagnostic criteria for Kleine-Levin syndrome (ICSD-3).

A at least two recurrent episodes of excessive sleepiness, each persisting for 2 days to 5 weeks,
B episodes recur at least 1 per 18 months
C normal alertness, cognitive function, behavior, and mood between episodes
In addition to the recurrent hypersomnia, the patient should also have at least one of the following:
1. Hyperphagia
2. Hypersexuality
3. Abnormal behavior—irritability, aggression
4. Cognitive abnormalities—ex confusion, derealization, hallucinations
5. Hypersomnolence and related symptoms are not better explained by another sleep disorder, other medical, neurologic, or psychiatric disorder (especially bipolar disorder), or use of drugs or medications.