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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Nature. 2021 Mar 17;592(7856):778–783. doi: 10.1038/s41586-021-03350-4

Extended Data Fig. 1 |. Structure determination of the NLRP1-DPP9 complex.

Extended Data Fig. 1 |

a, Purification of the NLRP1-DPP9 complex by ion exchange chromatography. The ternary complex peak is shaded in green and labelled with an arrow. b, A representative (>1000 images) cryo-EM micrograph. c, Representative 2D class averages. d, Workflow for the NLRP1-DPP9 complex structure determination. e, Map-map and map-model FSC curves. f, Local resolution distribution of the final map calculated with ResMap45 and coloured as indicated.