Figure 3. Expression of phenotypic markers by TRM CD4 T cells.

a) Expression of CD62L, CXCR3, and CD122 by CD69⁺CD103⁻ CD49d⁺CD11a^hi CD4 T cells was compared to circulating (IV⁺) CD49d⁺CD11a^hi CD4 T cells. Representative histograms from day 30 p.i. are shown. b) Frequency and c) number of CD62L⁺ cells in the lung. d) Frequency and e) number of CXCR3⁺ cells in the lung. f) Frequency and g) number of CD122⁺ cells in the lung. Data are represented as mean ± SEM from two independent experiments that have been combined (n=3–4 mice per experiment). Statistical analysis was performed with Student’s t test, * p<0.05, ** p<0.01, *** p<0.001.