Table 2.
Pathological characteristics of AAV patients in different AKI stages.
| Stage 1 (n = 32) | Stage 2 (n = 31) | Stage 3 (n = 33) | P-value | |
|---|---|---|---|---|
| Global sclerosis1, Median (IQR) | 20.3 (10.0, 38.5) | 21.1 (12.5, 36.4) | 15.4 (7.1, 20.8) | 0.510 |
| Crescent1, Median (IQR) | 11.9 (5.7, 34.1) | 16.1 (10.9, 33.4) | 21.2 (14.3, 51.7) ** | 0.043 |
| Cellular crescent1, Median (IQR) | 5.8 (0.0, 21.4) | 8.0 (2.0, 13.4) | 15.2 (5.7, 26.7) | 0.075 |
| Capillary Necrosis, n (%) | 12 (37.5) | 11 (35.4) | 19 (57.5) | 0.140 |
| Mesangial hypercellularity, n (%) | 32 (100.0) | 31 (100.0) | 32 (96.970) | 0.381 |
| Endocapillary hypercellularity, n (%) | 9 (28.1) | 13 (41.9) | 16 (48.5) | 0.232 |
| Interstitial fibrosis, n (%) | 0.399 | |||
| 0–50% | 26 (81.2) | 22 (71.0) | 22 (66.7) | |
| >50% | 6 (18.8) | 9 (29.0) | 11 (33.3) | |
| Interstitial infiltration, n (%) | 0.269 | |||
| 0–25% | 11 (34.4) | 4 (12.9) | 8 (24.2) | |
| 25–50% | 11 (34.4) | 11 (35.5) | 9 (27.3) | |
| >50% | 10 (31.2) | 16 (51.6) | 16 (48.5) |
1Proportion of glomeruli per biopsy with the lesion, data was expressed as median and interquartile range (IQR).
**P < 0.01, compared with AKI stage 1.
Bolded value: P-value < 0.05.