Table 1.
Baseline characteristics in the total cohort (A) and the subgroup of patients with septic shock (B) stratified for age categories into old and very old septic patients.
| A Total cohort | B Septic shock | |||||
|---|---|---|---|---|---|---|
| Old (>64 years) | Very old (>79 years) | p-value | Old (>64 years) | Very old (>79 years) | p-value | |
| n = 6,184 | n = 3,201 | n = 730 | n = 324 | |||
| Age (years); median (IQR) | 72 (8) | 84 (4) | <0.001 | 72 (8) | 84 (4) | <0.001 |
| male; n (%) | 3,221 (52) | 1,638 (51) | 0.40 | 384 (53) | 177 (55) | 0.54 |
| BMI; median (IQR) | 28 (10) | 25 (8) | 0.001 | 27 (10) | 25 (8) | <0.001 |
| BMI <18.5 | 289 (14) | 217 (15) | 0.48 | 29 (12) | 24 (15) | 0.31 |
| BMI > 30 | 2,243 (56) | 740 (40) | <0.001 | 255 (54) | 75 (36) | <0.001 |
| SOFA score; median (IQR) | 6 (5) | 6 (5) | 0.66 | 10 (5) | 9 (4) | 0.007 |
| Creatinine (mg/dl); median (IQR) | 1.4 (1.5) | 1.5 (1.3) | 0.005 | 2.1 (1.6) | 1.9 (1.5) | 0.13 |
| Creatinine >2.0mg/dl | 1,809 (31) | 911 (31) | 0.82 | 369 (52) | 142 (46) | 0.052 |
| Lactate (mmol/L); median (IQR) | 1.8 (1.8) | 2.0 (1.9) | 0.02 | 3.8 (3.5) | 3.7 (3.1) | 0.18 |
| Infection focus | ||||||
| UTI; n (%) | 1,490 (24) | 887 (28) | <0.001 | 158 (21) | 90 (28) | 0.03 |
| Pulmonary; n (%) | 2,407 (39) | 1,264 (40) | 0.60 | 261 (36) | 102 (32) | 0.18 |
| GI; n (%) | 730 (12) | 382 (12) | 0.85 | 142 (20) | 50 (15) | 0.12 |
| Cutaneous; n (%) | 477 (8) | 160 (5) | <0.001 | 32 (4) | 16 (5) | 0.69 |
| Unknown; n (%) | 704 (11) | 328 (10) | 0.10 | 95 (13) | 44 (14) | 0.80 |
| Gynaecologic; n (%) | 7 (<1) | 0 (0) | 0.06 | 1 (<1) | 0 (0) | 0.51 |
| Other; n (%) | 369 (6) | 180 (6) | 0.50 | 41 (6) | 22 (7) | 0.46 |
SOFA, Sepsis-related organ failure assessment; BMI, body mass index; UTI, urinary tract infection; GI, gastrointestinal.