Table 3.
Associations of old vs. very old septic patients with mortality and management strategies in three multi-level logistic regression models.
| Total cohort | |||||
|---|---|---|---|---|---|
| Crude events | |||||
| Old | Very old | Model 1 | Model 2 | Model 3 | |
| n (%) | n (%) | aOR (95% CI, p-value) | aOR (95% CI, p-value) | aOR (95% CI, p-value) | |
| ICU mortality | 692 (11) | 412 (13) | 1.21 (1.06–1.38; 0.005) | 1.28 (1.06–1.54; 0.01) | 1.32 (1.09–1.59; 0.004) |
| Management | – | – | – | – | – |
| Mechanical ventilation | 1,418 (23) | 562 (18) | 0.72 (0.64–0.81; <0.001) | 0.72 (0.61–0.85; <0.001) | – |
| Vasopressor use | 2,075 (34) | 1,045 (33) | 0.99 (0.90–1.10; 0.91) | 0.99 (0.86–1.14; 0.86) | – |
Model 1, ICU cluster as random effect; Model 2, Model 1 plus patient level (SOFA, BMI, sex, ethnics, infection focus, lactate concentration); Model 3, Model 2 plus management strategies (mechanical ventilation, vasopressor use); SOFA, Sepsis-related organ failure assessment; BMI, body mass index.