Table 4.
Association of old vs. very old septic shock patients with mortality and management strategies in three multi-level logistic regression models.
| Septic shock patients | |||||
|---|---|---|---|---|---|
| Crude events | |||||
| Old | Very old | Model 1 | Model 2 | Model 3 | |
| n (%) | n (%) | aOR (95% CI, p-value) | aOR (95%CI, p-value) | aOR (95% CI, p-value) | |
| ICU mortality | 260 (36) | 122 (38) | 1.10 (0.84–1.45; 0.49) | 1.46 (1.07–1.99; 0.02) | 1.50 (1.10–2.06; 0.01) |
| Management | – | – | – | – | – |
| Mechanical ventilation | 404 (55) | 136 (42) | 0.60 (0.46–0.79; <0.001) | 0.68 (0.49–0.93; 0.02) | – |
| Vasopressor use | 730 (100) | 324 (100) | – | – | – |
Model 1, ICU cluster as random effect; Model 2, Model 1 plus patient level (SOFA, BMI, sex, ethnics, infection focus, lactate concentration); Model 3, Model 2 plus management strategies (mechanical ventilation, vasopressor use); SOFA, Sepsis-related organ failure assessment; BMI, body mass index.