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. 2021 Jul 9;9:640958. doi: 10.3389/fcell.2021.640958

FIGURE 2.

FIGURE 2

Notch3 expression in proliferative niches of 7-weeks-old (A: A–G) vs. 25-weeks-old (B: A–F) N. furzeri brain. (A) (A,B) Overview of the brain in horizontal medial section (along the dorso/ventral axis) stained for notch1a, respectively, in telencephalon (A) and optic tectum (OT) (B) regions of a young N. furzeri brain (7 weeks). White frames show the areas magnified in panels (C–G), representing, respectively, the anterior (aTel), central (cTel), and lateroposterior (lpTel) telencephalic regions and the anterior (aOT) and posterior optic tectum regions. (B) (A–C) Overview of the brain in horizontal medial section (along the dorso/ventral axis) stained for notch3, respectively, in the anterior (A) and lateroposterior (B) telencephalon and the posterior optic tectum (pOT) (C) regions of an old N. furzeri brain (25 weeks). White frames show the areas magnified in panels (D–I), representing, respectively, the anterior (aTel), central (cTel), lateral (lTel), and posterior (pTel) telencephalic regions and the anterior (aOT) and posterior (pOT) optic tectum regions. Scale bars always represent 50 μm and are indicative for all further images without specific scale bar indication. Brain drawings on the left (modified from D’angelo, 2013–Atlas) represent the horizontal overview of the whole killifish brain; red-squared areas indicate the position of the figure panels based on the corresponding letters.