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. 2021 Jul 9;9:690186. doi: 10.3389/fbioe.2021.690186

FIGURE 7.

FIGURE 7

Expressions of NLRC5 correlates positively with cytotoxic signature in melanoma datasets. (A–D) Spearman correlation analysis of the NLRC5 expression and cytotoxic score in TCGA SKCM, GSE54467, GSE59455, and GSE65904, respectively. (E–H) Spearman correlation analysis of the NLRC5 and GZMA expression in TCGA SKCM, GSE54467, GSE59455, and GSE65904, respectively. (I–L) Spearman correlation analysis of the NLRC5 expression and PRF1 expression in TCGA SKCM, GSE54467, GSE59455, and GSE65904, respectively. (M–P) Spearman correlation analysis of the NLRC5 expression and infiltrating level of CD8+ T cells in TCGA SKCM, GSE54467, GSE59455, and GSE65904, respectively. (Q–T) Spearman correlation analysis of the NLRC5 expression and GZMA expression, PRF1 expression, cytotoxic CD8+ T cell signature score, CD8+ T cell signature score in “Liu et al., Nat Medicine 2019,” respectively. Spearman r and p-value for each correlation are shown.