Table 3. Cardiovascular Assessments for Patients Receiving TKIs for CML-CP.
| Assessment | Imatinib | Dasatinib | Nilotinib | Bosutinib | Ponatinib |
|---|---|---|---|---|---|
| Baseline | |||||
| Clinical CV assessment | Y | Y | Y | Y | Y |
| Blood pressure | Y | Y | Y | Y | Y |
| Fasting glucose | AI | AI | Y | AI | Y |
| Fasting lipids | AI | AI | Y | AI | Y |
| Electrocardiogram | Y | Y | Y | Y | Y |
| Echocardiogram | AI | AI | AI | AI | AI |
| Ankle-brachial index | AI | AI | AI | AI | AI |
| 1-month follow-up | |||||
| Clinical CV assessment | AI | Y | Y | AI | Y |
| Blood pressure | AI | AI | AI | AI | Y |
| 3- to 6-month follow-upa | |||||
| Clinical CV assessment | Y | Y | Y | Y | Y |
| Blood pressure | AI | AI | Y | AI | Y |
| Fasting glucose | AI | AI | Y | AI | AI |
| Fasting lipids | AI | AI | Y | AI | Y |
| Electrocardiogram | AI | AI | Y | AI | Y |
| Echocardiogram | AI | AI | AI | AI | AI |
| Ankle-brachial index | AI | AI | AI | AI | AI |
Note. Assessments should be performed more frequently in patients with high cardiovascular risk or if clinically indicated. AI = as indicated; CV = cardiovascular; Y = yes. Table adapted with permission from Barber et al. (2017)
Follow-ups should continue every 3–6 months and at least yearly for patients in stable condition.