Table 5.
Cox Regression Model for Predicting MACE in ACS Patients Undergoing PCI.
| Variables | Univariate | Multivariate model 1 | Multivariate model 2 | Multivariate model 3 | Multivariate model 4 | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | |
| ≥65 years old | 3.314 (2.005-5.478) | <0.001 | 2.905 (1.699-4.968) | <0.001 | 2.930 (1.705-5.035) | <0.001 | 2.881 (1.682-4.934) | <0.001 | 2.788 (1.638-4.744) | <0.001 |
| HF | 4.588 (2.666-7.896) | <0.001 | 2.296 (1.213-4.347) | 0.011 | 2.083 (1.083-4.008) | 0.028 | 2.263 (1.190-4.303) | 0.013 | 2.306 (1.200-4.429) | 0.012 |
| CGS | 11.432 (5.415-24.136) | <0.001 | 4.327 (1.738-10.774) | 0.002 | 5.396 (2.113-13.778) | <0.001 | 5.319 (2.119-13.349) | <0.001 | 4.682 (1.830-11.979) | 0.001 |
| Cr > 110 μmol/L | 4.157 (1.788-9.664) | <0.001 | 4.726 (1.992-11.214) | <0.001 | 4.732 (1.991-11.249) | <0.001 | 4.332 (1.820-10.315) | <0.001 | - | - |
| LVEF <40% | 6.897 (3.252-14.629) | <0.001 | 3.853 (1.614-9.046) | 0.002 | 3.617 (1.511-8.661) | 0.004 | 3.337 (1.418-7.851) | 0.006 | 3.324(1.370-8.063) | 0.008 |
| SII ≥ 628.60 | 2.558 (1.487-4.401) | <0.001 | 2.545 (1.416-4.574) | 0.002 | - | - | - | - | - | - |
| dNLR ≥ 2.29 | 2.572 (1.507-4.392) | <0.001 | - | - | 2.610 (1.454-4.685) | 0.001 | - | - | - | - |
| NLR ≥ 2.67 | 2.857 (1.594-5.118) | <0.001 | - | - | - | - | 2.927 (1.530-5.602) | 0.001 | - | - |
| PLR ≥ 237.93 | 2.704 (1.526-4.790) | <0.001 | - | - | - | - | - | - | 2.118 (1.147-3.911) | 0.017 |
Abbreviations: MACE, major adverse cardiovascular events; ACS, acute coronary syndrome; PCI, percutaneous coronary intervention; CI, confidence interval; HF, heart failure; CGS, cardiogenic shock; Cr, creatinine; LVEF, left ventricular ejection fraction; SII, systemic immune-inflammation index; dNLR, derived neutrophil-to-lymphocyte ratio; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio.