. 2021 Jul 9;12:705758. doi: 10.3389/fmicb.2021.705758

TABLE 5.

Effects of P8 on the expressions of intestinal tight junction proteins and levels of D-lactate and diamine oxidase of Eimeria-infected broilers at days 21 and 42.

	NC	IC	P8L	P8H	DIC	SEM	P-value
Day 21
Claudin-1	0.788^b	0.366^c	0.673^b	0.787^b	0.970^a	0.042	0.000
Occludin	0.755^b	0.380^d	0.560^c	0.761^b	0.923^a	0.038	0.000
D-lactate (μmol/L)	53.76^b	77.82^a	62.67^b	56.24^b	61.91^b	2.031	0.001
Diamine oxidase (ng/ml)	19.55^c	30.68^a	24.64^b	22.83^b	21.88^bc	0.706	0.000
Day 42
Claudin-1	0.474^ab	0.201^c	0.368^b	0.502^ab	0.594^a	0.032	0.000
Occludin	0.629^ab	0.282^d	0.452^c	0.548^bc	0.725^a	0.035	0.000
D-lactate (μmol/L)	49.87^b	76.88^a	56.78^b	53.89^b	53.01^b	2.268	0.000
Diamine oxidase (ng/ml)	16.89^b	24.50^a	20.77^ab	17.22^b	17.78^b	0.712	0.001

^a,b,c,dMean value within a role with no common superscript differ significantly (P < 0.05). NC, control diet; IC, control diet + Eimeria infection; P8L, control diet containing 1 × 10⁷ cfu/g P8 + Eimeria infection; P8H, control diet containing 1 × 10⁸ cfu/g P8 + Eimeria infection; DIC, control diet + Eimeria infection + Diclazuril.