Table 5.
Dosimetry comparison of [89Zr]Zr-PCTA, [89Zr]Zr-TRITA and [89Zr]Zr-NOTA
| Tissue/Organ | Dose per Administered Activity (mGy/MBq) | ||||
|---|---|---|---|---|---|
| [89Zr]Zr-DFO | [89Zr]Zr-DOTA | [89Zr]Zr-NOTA | [89Zr]Zr-PCTA | [89Zr]Zr-TRITA | |
| Brain | 2.0 | 1.8 | 2.2 | 2.1 | 54.6 |
| Large Intestine | 3.1 | 21.0 | 17.1 | 8.5 | 28.8 |
| Small Intestine | 2.0 | 5.0 | 4.7 | 2.8 | 16.8 |
| Stomach Wall | 15.6 | 19.1 | 10.7 | 41.1 | 55.6 |
| Heart | 2.1 | 2.0 | 2.4 | 2.2 | 53.3 |
| Kidneys | 2.0 | 2.7 | 2.7 | 2.1 | 16.2 |
| Liver | 2.1 | 2.2 | 2.4 | 2.3 | 33.4 |
| Lung | 3.1 | 2.3 | 3.0 | 3.4 | 151.0 |
| Pancreas | 4.3 | 3.3 | 3.2 | 2.7 | 16.6 |
| Skeleton | 8.5 | 4.2 | 6.9 | 10.2 | 679.0 |
| Spleen | 8.4 | 3.0 | 3.3 | 3.3 | 17.9 |
| Testes | 2.0 | 2.2 | 2.4 | 2.0 | 13.9 |
| Thyroid | 2.4 | 2.1 | 2.6 | 2.5 | 76.0 |
| Urinary Bladder | 29.9 | 30.3 | 30.4 | 30.0 | 41.6 |
| Total Body | 2.3 | 2.4 | 2.7 | 2.5 | 65.0 |