Figure 1.

Significant positive correlation between vitreous fluid levels of sCD146 and levels of VEGF (Spearman's correlation coefficient), as measured by specific ELISAs (panel A). Determination of sCD146 levels in vitreous fluid samples. Equal volumes (15 µl) of vitreous fluid samples from patients with proliferative diabetic retinopathy (PDR; n = 10) and from nondiabetic patients with rhegmatogenous retinal detachment (RD; n = 8) were subjected to gel electrophoresis and the presence of sCD146 was detected by Western blot analysis. A representative set of samples is shown (panel B). The intensity of the protein band was determined in all samples (panel C). sCD146 band intensities were compared between the RD and PDR groups. Results are expressed as median (interquartile range). (p = 0.005; Mann-Whitney test).