Table 1.
Study | Cows, n | Dose 1 | Delivery Method | Outcomes Measured | References |
---|---|---|---|---|---|
Mezzetti et al., 2019 | 38 | 335 | CRC 2 | Rumen fluid: pH, ammonia, VFA 3, immunoglobulins, lymphocytes, myeloid cells | [19] |
Schären et al., 2017 | 60 | 335 | CRC | Rumen fluid: LPS, ammonia, VFA, microbiome characterization | [18] |
Drong et al., 2016 | 60 | 335 | CRC | Individual DMI, rumen pH, ammonia, VFA, protozoa count | [20] |
McCarthy et al., 2015b | 70 | 400 pre partum 450 post partum |
Top-dressing | Individual DMI, total dry matter, NDF and starch digestibility | [21] |
Mullins et al., 2012 | 32 | 400 pre partum 450 post partum |
Top-dressing | Individual DMI, meal frequency, rumen pH | [22] |
Fairfield et al., 2007 | 16 | 335 | CRC | Individual DMI, pH. | [23] |
Petersson-Wolfe et al., 2007 | 136 | 335 | CRC | Individual DMI | [24] |
Zahra et al., 2006 | 182 | 335 | CRC | Individual DMI | [25] |
Plaizier et al., 2000 | 16 | 335 | CRC | Individual DMI, NDF digestibility, rumen ammonia content | [26] |
Green et al., 1999 | 52 | 335 | CRC | Rumen ph, ammonia, VFA | [27] |
1 Daily dose (mg/day); 2 controlled-release capsule; 3 volatile fatty acids.