Table 5.
Effect of dietary GHBP on serum biochemical parameters of broiler chickens.
| Parameter | Control | GHBP100 | GHBP200 | GHBP300 | SEM | p-Value |
|---|---|---|---|---|---|---|
| ALT, U/L | 37.9 | 36.8 | 36.2 | 39.1 | 0.520 | 0.217 |
| AST, U/L | 36.6 | 34.3 | 33.1 | 33.2 | 0.650 | 0.210 |
| Uric acid, μmol/L | 11.2 | 11.1 | 13.0 | 13.5 | 0.589 | 0.390 |
| Creatinine, mg/dL | 0.63 | 0.70 | 0.68 | 0.71 | 0.016 | 0.316 |
| Cholesterol, mg/dL | 98.4 a | 90.7 b | 89.9 b | 83.3c | 1.68 | <0.001 |
| TGs, mg/dL | 87.6 | 85.9 | 89.6 | 82.9 | 1.18 | 0.241 |
| HDL-C, mg/dL | 34.9 c | 41.1 b | 41.7 b | 52.0 a | 1.93 | <0.001 |
| LDL-C, mg/dL | 45.9 a | 32.4 b | 30.4 b | 14.7 c | 3.43 | <0.001 |
| VLDL-C, mg/dL | 17.5 | 17.2 | 17.9 | 16.6 | 0.235 | 0.241 |
| IGF-1 day 20, ng/mL | 9.53 c | 15.27 b | 18.50 a | 13.55 b | 1.01 | <0.001 |
| IGF-1 day 38, ng/mL | 10.73 c | 16.47 b | 19.70 a | 14.75 b | 1.00 | <0.001 |
| GH day 20, ng/mL | 6.87 b | 7.67 b | 10.07 a | 9.52 a | 0.438 | 0.003 |
| GH day 38, ng/mL | 8.80 c | 10.20 b | 12.30 a | 10.73 b | 0.390 | <0.001 |
a,b,c Means with different superscripts within the same row differ significantly (p < 0.05). GHBP: growth hormone-boosting peptide; ALT: alanine aminotransferase; AST: aspartate aminotransferase; TGs: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; VLDL-C: very-low density lipoprotein cholesterol; IGF-1: insulin-like growth factor 1; GH: growth hormone. Control: basal diet without GHBP; GHBP100: basal diet plus GHBP at a level of 100 μg/kg; GHBP200: basal diet plus GHBP at a level of 200 μg/kg; GHBP300: basal diet plus GHBP at a level of 300 μg /kg.