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. 2021 Jul 13;11(7):2082. doi: 10.3390/ani11072082

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Differentially abundant genera in the pig gut microbiota among the four treatment groups orally vaccinated with Lawsonia intracellularis vaccine at week 6. The linear discriminant analysis (LDA) effect size (LEfSe) algorithm is used for biomarker discovery, which emphasizes both statistical and biological relevance. A p-Value of <0.05 is considered significant in Kruskal–Wallis and pairwise Wilcoxon tests, respectively. The LDA score for discriminative features is 3. The length of the histogram represents the LDA score, which explains the degree of influence of species with significant difference among the four treatment groups (CONT, LAW1, LAW2, and LAW3).