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. 2021 Jul 22;11(7):e048086. doi: 10.1136/bmjopen-2020-048086

Table 2.

Overall association of county-level Social Vulnerability Index (IRR per 10 percentile increase) with incidence and death per capita of COVID-19 as of 6 March 2021

Model 1* Model 2† Model 3‡
IRR (95% CI) P value IRR (95% CI) P value IRR (95% CI) P value
Incidence
Overall Social Vulnerability Index§ 1.03 (1.03 to 1.04) <0.001 1.02 (1.02 to 1.03) <0.001 1.02 (1.02 to 1.03) <0.001
Socioeconomic status 1.02 (1.02 to 1.03) <0.001 1.02 (1.01 to 1.02) <0.001 1.02 (1.01 to 1.02) <0.001
Minority status and language 1.02 (1.01 to 1.02) <0.001 1.02 (1.01 to 1.02) <0.001 1.02 (1.01 to 1.02) <0.001
Housing type and transport 1.01 (1.00 to 1.01) 0.003 0.99 (0.99 to 1.00) 0.07 0.99 (0.99 to 1.00) 0.29
Household composition and disability§ 1.02 (1.01 to 1.02) <0.001 1.01 (1.01 to 1.02) <0.001 1.01 (1.01 to 1.02) <0.001
Death per capita
Overall Social Vulnerability Index§ 1.07 (1.06 to 1.08) <0.001 1.05 (1.04 to 1.06) <0.001 1.04 (1.04 to 1.05) <0.001
Socioeconomic status 1.07 (1.07 to 1.08) <0.001 1.05 (1.04 to 1.06) <0.001 1.05 (1.04 to 1.05) <0.001
Minority status and language 1.03 (1.02 to 1.03) <0.001 1.01 (1.00 to 1.02) 0.003 1.01 (1.00 to 1.02) 0.004
Housing type and transport 1.06 (1.05 to 1.06) <0.001 1.05 (1.04 to 1.05) <0.001 1.05 (1.04 to 1.05) <0.001
Household composition and disability§ 1.04 (1.03 to 1.05) <0.001 1.02 (1.01 to 1.02) <0.001 1.02 (1.01 to 1.02) <0.001

*Base model: adjusted for proportion of population aged ≥65 years and state-level COVID-19 testing.

†Base model+CMS average HCC score (proxy for comorbidities).

‡Base model+CMS average HCC score (proxy for comorbidities)+environmental factors including average daily temperature (degrees Fahrenheit), average daily precipitation and average particulate matter of diameter ≥2.5 μm.

§Proportion aged ≥65 years not included as a covariate for models for overall Social Vulnerability Index and household composition/disability because these indices contain the age variable.

CMS, Centers for Medicare and Medicaid Services; HCC, Hierarchical Condition Category; IRR, incidence rate ratio.