Table 1.
Baseline characteristics of patients with AF undergoing TAVR discharged on OAC alone, APT alone, or OAC+APT therapy
| OAC Alone N=763 | APT Alone N=4786 | OAC+APT N=5833 | p-value | |
|---|---|---|---|---|
| Age, years | 85.0 (79.0–88.0) | 85.0 (79.0–89.0) | 84.0 (79.0–88.0) | <.001 |
| Female | 406 (53.2%) | 2,100 (43.9%) | 2,676 (45.9%) | <.001 |
| White Race | 734 (96.8%) | 4,628 (96.9%) | 5,699 (98.1%) | <.001 |
| STS PROM Score, % | 7.4 (5.2–11.1) | 8.3 (5.6–12.3) | 7.5 (5.2–11.2) | <.001 |
| CHADS2-Vasc Score, median (IQR) | 5.0 (4.0–6.0) | 5.0 (5.0–6.0) | 5.0 (5.0–6.0) | 0.007 |
| ATRIA Score, median (IQR) | 6.0 (3.0–6.0) | 6.0 (3.0–6.0) | 6.0 (3.0–6.0) | <.001 |
| NYHA Class III/IV within 2 Weeks | 624 (82.4%) | 3,956 (83.6%) | 4,911 (84.9%) | 0.075 |
| Coronary Artery Disease | 302 (39.7%) | 2,953 (61.8%) | 3,284 (56.4%) | <.001 |
| Prior Open Heart Surgery | 223 (29.2%) | 1,654 (34.6%) | 1,992 (34.2%) | 0.013 |
| Prior Aortic Valve Procedure | 107 (14.0%) | 851 (17.8%) | 836 (14.3%) | <.001 |
| Prior Stroke | 119 (15.6%) | 604 (12.6%) | 849 (14.6%) | 0.005 |
| Peripheral Arterial Disease | 205 (27.0%) | 1,498 (31.4%) | 1,788 (30.7%) | 0.053 |
| Severe COPD | 89 (11.8%) | 696 (14.7%) | 882 (15.2%) | 0.041 |
| Oxygen-Dependent Lung Disease | 92 (12.1%) | 697 (14.6%) | 773 (13.3%) | 0.056 |
| Current Dialysis | 20 (2.6%) | 229 (4.8%) | 158 (2.7%) | <.001 |
| Permanent Pacemaker/ICD | 238 (31.2%) | 1,294 (27.0%) | 1,833 (31.4%) | <.001 |
| Hostile Chest | 53 (7.0%) | 344 (7.2%) | 427 (7.3%) | 0.920 |
| Porcelain Aorta | 45 (5.9%) | 233 (4.9%) | 348 (6.0%) | 0.043 |
| LVEF < 30% | 56 (7.5%) | 362 (7.7%) | 495 (8.6%) | 0.199 |
| Femoral Access | 592 (78.5%) | 3,466 (72.7%) | 4,332 (74.6%) | 0.002 |
STS PROM = Society of Thoracic Surgeons Predicted Risk of Mortality at 30 days; CHADs2- VASC = congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, stroke or transient ischemic attack (TIA), vascular disease, age 65 to 74 years, sex category; ATRIA = Anticoagulation and Risk Factors in Atrial Fibrillation; NYHA = New York Heart Association Functional Class;