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. 2021 Jun 27;10(7):781. doi: 10.3390/antibiotics10070781

Figure 2.

Figure 2

In vitro analyses of MVB (A) and MVB + FOS (B,C) against KPC-Kp strain isolated from the blood. Gradient strip test (E-test) showed MVB MIC of 0.38 μg/mL (Panel A). Synergy tests showed that, in the presence of 0.5×MIC (8 μg/mL) and 0.25×MIC (4 μg/mL) of FOS, MVB MICs lowered to 0.016 and 0.023 μg/mL, respectively. FOS MIC was determined with agar dilution method and was 16 μg/mL (image not shown). Arrows indicate MVB MIC in the presence of FOS. MVB: meropenem/vaborbactam; FOS: fosfomycin. In the lower part of the figure, there is a magnification of the MVB MIC value in the presence of FOS.