Table 1.
Baseline demographic and clinical characteristics of study participants who completed the final assessment.
| Characteristics | Placebo (n = 26) |
Mel-Zinc (n = 24) |
p-Value |
|---|---|---|---|
| Age (years) | 53.7 ± 9.6 | 51.0 ± 10.2 | 0.339 |
| Marital status | 0.473 | ||
| Married | 15 (58) | 16 (70) | |
| Single | 7 (27) | 6 (26) | |
| Separated/divorced | 4 (15) | 1 (4) | |
| BMI (kg/m2) | 28 ± 0.1 | 26 ± 0.3 | 0.651 |
| Systolic BP (mmHg) | 118 ± 17.1 | 114 ± 13.7 | 0.291 |
| Diastolic BP (mmHg) | 78 ± 11.9 | 72 ± 9.1 | 0.088 |
| Heart rate (bpm) | 75 ± 8 | 76 ± 12 | 0.680 |
| Illness duration (years) | 0.201 | ||
| >10 | 17 (65) | 19 (79) | |
| ≤10 | 6 (23) | 4 (17) | |
| History of chronic pain | 25 (96) | 24 (100) | 0.319 |
| Illness-affected relatives | 11 (42) | 5 (21) | 0.135 |
| Concomitant drugs | |||
| Anticonvulsants | 13 (50) | 18 (75) | 0.217 |
| Antidepressants | 19 (73) | 24 (85) | 0.065 |
| Anxiolytics | 5 (19) | 6 (25) | 0.302 |
| NSAID | 12 (46) | 11 (46) | 0.720 |
| Opioids | 9 (34) | 12 (50) | 0.547 |
Data are expressed as the mean ± SD for continuous variables and compared by Student’s t-test, and categorical variables are given as numbers with percentages (%) and compared by Fisher’s exact test. Abbreviations: Mel-Zinc, Melatonin plus Zinc group; BMI, body mass index; BP, blood pressure; NSAID, non-steroidal anti-inflammatory drugs.